A review on migraine and oxidative stress

Autores

Resumo

Migraine is a highly prevalent disease, with important personal and socioeconomic impacts, but its pathophysiology is still poorly understood. Dysfunctions of trigeminovascular system and the phenomenon of cortical spreading depression are the main known mechanisms. The oxidative imbalance at the cellular level seems to be a possible mechanism for triggering phenomena that lead to migraine crisis. The present article presents a systematic review of studies on oxidative stress markers in 2613 migraine patients, with most studies showing signs of oxidative imbalance, especially of the nitric oxide and malondialdehyde systems.

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Biografia do Autor

Marco Agassiz Almeida Vasques, Hospital das Forças Armadas

Neurocirurgião, Hospital das Forças Armadas

Divisão de Pesquisas / DTEP / HFA

Eliana de Barros Marques Fonseca, Hospital das Forças Armadas

Neuropediatra

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Publicado

2020-11-02