Parkinson Disease and Its Clinical Manifestations

Raphael Lopes Olegário, Jerrime Bernard Fobbs, Bruno Sousa Lopes, Paulinne Junqueira Silva Andresen Strini, Polyanne Junqueira Silva Andresen Strini, Lídia Mara Aguiar Bezerra de Melo


Parkinson's disease (PD) is a neurodegenerative disorder that leads to progressive deterioration of motor function due to loss of dopamine-producing brain cells. Symptoms generally develop slowly over years. The progression of symptoms varies from person-to-person due to the diversity of the disease. Although there is no cure yet, multiple treatment options ranging from prescription dispensing, disease management and/or medication therapy management and surgery exists as a means to help patients living with this disease. Parkinson’s itself is not fatal, however, complications that arise as consequence of this disorder can be serious. The diagnosis of PD within a patient is based upon its distinctive clinical features discerned from the patient’s medical history and neurologic examination. At a minimum, bradykinesia coupled with either tremors or rigidity must be present in order to consider diagnosing a person with PD.

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